With United and West Ham facing tough trips to City and Liverpool, Arsenal may end the weekend back in the top four.
The Gunners have not qualified for the Champions League since the 2015-16 campaign. But with games in hand they are in the driving seat to do just that under Mikel Arteta.
Speaking exclusively to LiveScore at the London Football Awards, Alan Smith and George Graham gave their thoughts on the North London club’s bid to secure a place at European football’s top table.
The big games do not stop in the fascinating Serie A title race as joint-leaders Napoli and AC Milan meet at the Stadio Diego Armando Maradona on Sunday night.
Their clash opens the door for Inter Milan, two points behind them, to take advantage as they welcome rock-bottom Salernitana to the San Siro tonight.